Richard R. Tidwell

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pathology, Microbiology Biology
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"Richard Tidwell"
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Publications

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Alghamdi A, Munday JC, Campagnaro GD, et al. (2020) Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter . Elife. 9
Gillingwater K, Kunz C, Braghiroli C, et al. (2017) In vitro, Ex vivo and In vivo Activity of Diamidines against Trypanosoma congolense and Trypanosoma vivax. Antimicrobial Agents and Chemotherapy
Patrick DA, Wenzler T, Yang S, et al. (2016) Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense. Bioorganic & Medicinal Chemistry
Pohlig G, Bernhard SC, Blum J, et al. (2016) Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial. Plos Neglected Tropical Diseases. 10: e0004363
Burri C, Yeramian PD, Allen JL, et al. (2016) Efficacy, Safety, and Dose of Pafuramidine, a New Oral Drug for Treatment of First Stage Sleeping Sickness, in a Phase 2a Clinical Study and Phase 2b Randomized Clinical Studies. Plos Neglected Tropical Diseases. 10: e0004362
Guedes-Da-Silva FH, Batista DGJ, Meuser MB, et al. (2016) In vitro and in vivo trypanosomicidal action of novel arylimidamides against trypanosoma cruzi Antimicrobial Agents and Chemotherapy. 60: 2425-2434
Thuita JK, Wolf KK, Murilla GA, et al. (2015) Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys. Plos Neglected Tropical Diseases. 9: e0003409
Wenzler T, Yang S, Patrick DA, et al. (2014) In vitro and in vivo evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness. Antimicrobial Agents and Chemotherapy. 58: 4452-63
Timm BL, da Silva PB, Batista MM, et al. (2014) In vitro and in vivo biological effects of novel arylimidamide derivatives against Trypanosoma cruzi. Antimicrobial Agents and Chemotherapy. 58: 3720-6
Patrick DA, Bakunov SA, Bakunova SM, et al. (2014) Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & Medicinal Chemistry. 22: 559-76
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