Owen W. Griffith

Affiliations: 
Medical College of Wisconsin, Milwaukee, WI, United States 
Area:
Biochemistry, Microbiology Biology
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"Owen Griffith"
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Publications

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Nakashima Y, Nii H, Janowiak BE, et al. (2009) Crystallization and preliminary crystallographic analysis of bifunctional -glutamylcysteine synthetase-glutatione synthetase from Streptococcus agalactiae Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 678-680
Janowiak BE, Hayward MA, Peterson FC, et al. (2006) γ-glutamylcysteine synthetase-glutathione synthetase: Domain structure and identification of residues important in substrate and glutathione binding Biochemistry. 45: 10461-10473
Nilakantan V, Halligan NL, Nguyen TK, et al. (2005) Post-translational modification of manganese superoxide dismutase in acutely rejecting cardiac transplants: role of inducible nitric oxide synthase. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 24: 1591-9
Janowiak BE, Griffith OW. (2005) Glutathione synthesis in Streptococcus agalactiae: One protein accounts for γ-glutamylcysteine synthetase and glutathione synthetase activities Journal of Biological Chemistry. 280: 11829-11839
Pieper GM, Nilakantan V, Hilton G, et al. (2004) Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection American Journal of Physiology - Heart and Circulatory Physiology. 286: H525-H534
Brenot A, King KY, Janowiak B, et al. (2004) Contribution of Glutathione Peroxidase to the Virulence of Streptococcus pyogenes Infection and Immunity. 72: 408-413
Bretscher LE, Li H, Poulos TL, et al. (2003) Structural Characterization and Kinetics of Nitric-oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N 5-(Iminoalkenyl)-ornithines Journal of Biological Chemistry. 278: 46789-46797
Kelly BS, Antholine WE, Griffith OW. (2002) Escherichia coli γ-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding Journal of Biological Chemistry. 277: 50-58
Raman CS, Li H, Martásek P, et al. (2001) Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase Journal of Biological Chemistry. 276: 26486-26491
Shi Y, Pritchard KA, Holman P, et al. (2000) Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. Free Radical Biology & Medicine. 29: 695-703
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