Joseph A. Krzycki

Ohio State University, Columbus, Columbus, OH 
Molecular Biology, Microbiology Biology
"Joseph Krzycki"


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Gregory Zeikus grad student 1985 Michigan State


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Donald J. Ferguson grad student 2000 Ohio State
Thomas C. Tallant grad student 2000 Ohio State
Gayathri Srinivasan grad student 2004 Ohio State
Sherry K. Blight grad student 2006 Ohio State
Anirban Mahapatra grad student 2007 Ohio State
Jitesh A. Soares grad student 2008 Ohio State
Marsha A. Gaston grad student 2011 Ohio State
Ruisheng Jiang grad student 2013 Ohio State
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Kountz DJ, Behrman EJ, Zhang L, et al. (2020) MtcB, a member of the MttB superfamily from the human gut acetogen Eubacterium limosum, is a cobalamin-dependent carnitine demethylase. The Journal of Biological Chemistry
Picking JW, Behrman EJ, Zhang L, et al. (2019) MtpB, a member of the MttB superfamily from the human intestinal acetogen , catalyzes proline betaine demethylation. The Journal of Biological Chemistry
Daly RA, Borton MA, Wilkins MJ, et al. (2016) Microbial metabolisms in a 2.5-km-deep ecosystem created by hydraulic fracturing in shales. Nature Microbiology. 1: 16146
Ticak T, Kountz DJ, Girosky KE, et al. (2014) A nonpyrrolysine member of the widely distributed trimethylamine methyltransferase family is a glycine betaine methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 111: E4668-76
Krzycki JA. (2013) The path of lysine to pyrrolysine. Current Opinion in Chemical Biology. 17: 619-25
Jiang R, Krzycki JA. (2012) PylSn and the homologous N-terminal domain of pyrrolysyl-tRNA synthetase bind the tRNA that is essential for the genetic encoding of pyrrolysine. The Journal of Biological Chemistry. 287: 32738-46
Ferguson T, Soares JA, Lienard T, et al. (2012) RamA, a protein required for reductive activation of corrinoid-dependent methylamine methyltransferase reactions in methanogenic Archaea (Journal of Biological Chemistry (2009) 284, (2285-2295)) Journal of Biological Chemistry. 287: 9328
Gaston MA, Jiang R, Krzycki JA. (2011) Functional context, biosynthesis, and genetic encoding of pyrrolysine. Current Opinion in Microbiology. 14: 342-9
Gaston MA, Zhang L, Green-Church KB, et al. (2011) The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine. Nature. 471: 647-50
Ferguson DJ, Longstaff DG, Krzycki JA. (2011) Assay of methylotrophic methyltransferases from methanogenic archaea. Methods in Enzymology. 494: 139-58
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