Tara L. Kieffer, Ph.D.

Affiliations: 
2005 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Immunology
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"Tara Kieffer"

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Robert F. Siliciano grad student 2005 Johns Hopkins
 (Mechanisms of HIV-1 persistence in the presence of highly active antiretroviral therapy (HAART).)
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Publications

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Kieffer TL, George S. (2014) Resistance to hepatitis C virus protease inhibitors. Current Opinion in Virology. 8: 16-21
Jiang M, Mani N, Lin C, et al. (2013) In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir. Antimicrobial Agents and Chemotherapy. 57: 6236-45
Adda N, Bartels DJ, Gritz L, et al. (2013) Futility rules for telaprevir combination treatment for patients with hepatitis C virus infection. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 11: 193-5
Bartels DJ, Sullivan JC, Zhang EZ, et al. (2013) Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment. Journal of Virology. 87: 1544-53
Thomas XV, de Bruijne J, Sullivan JC, et al. (2012) Evaluation of persistence of resistant variants with ultra-deep pyrosequencing in chronic hepatitis C patients treated with telaprevir. Plos One. 7: e41191
Kieffer TL, Sarrazin C, Miller JS, et al. (2007) Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients. Hepatology (Baltimore, Md.). 46: 631-9
Nettles RE, Kieffer TL. (2006) Update on HIV-1 viral load blips. Current Opinion in Hiv and Aids. 1: 157-61
Bailey JR, Sedaghat AR, Kieffer T, et al. (2006) Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells. Journal of Virology. 80: 6441-57
Nettles RE, Kieffer TL, Parsons T, et al. (2006) Marked intraindividual variability in antiretroviral concentrations may limit the utility of therapeutic drug monitoring. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 42: 1189-96
Lee PK, Kieffer TL, Siliciano RF, et al. (2006) HIV-1 viral load blips are of limited clinical significance. The Journal of Antimicrobial Chemotherapy. 57: 803-5
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