Moira A. McMahon, Ph.D.

Affiliations: 
2010 Johns Hopkins University, Baltimore, MD 
Area:
Pharmacology, Virology Biology
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"Moira McMahon"

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Robert F. Siliciano grad student 2010 Johns Hopkins
 (Characterizing unexpected inhibitors of HIV-1 replication.)
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Publications

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Voit RA, McMahon MA, Sawyer SL, et al. (2013) Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 786-95
McMahon MA, Rahdar M, Porteus M. (2012) Gene editing: not just for translation anymore. Nature Methods. 9: 28-31
McMahon MA, Parsons TL, Shen L, et al. (2011) Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. Journal of Virology. 85: 4618-22
Spivak AM, Rabi SA, McMahon MA, et al. (2011) Short communication: dynamic constraints on the second phase compartment of HIV-infected cells. Aids Research and Human Retroviruses. 27: 759-61
Kohli RM, Maul RW, Guminski AF, et al. (2010) Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification. The Journal of Biological Chemistry. 285: 40956-64
Kim HN, Wang J, Hughes J, et al. (2010) Effect of acyclovir on HIV-1 set point among herpes simplex virus type 2-seropositive persons during early HIV-1 infection. The Journal of Infectious Diseases. 202: 734-8
McMahon MA, Siliciano JD, Kohli RM, et al. (2010) Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs. Aids (London, England). 24: 319-23
McMahon MA, Shen L, Siliciano RF. (2009) New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo. Current Opinion in Infectious Diseases. 22: 574-82
McMahon MA, Siliciano JD, Lai J, et al. (2008) The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. The Journal of Biological Chemistry. 283: 31289-93
Shen L, Peterson S, Sedaghat AR, et al. (2008) Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nature Medicine. 14: 762-6
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