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Todd M. Lasco, Ph.D.

Affiliations: 
2002 Texas A & M University, College Station, TX, United States 
Area:
Microbiology Biology, Molecular Biology, Pathology
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David N. McMurray grad student 2002 Texas A & M
 (The role of tumor necrosis factor-alpha (TNF-alpha) in host resistance to experimental pulmonary tuberculosis.)

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Skeiky YA, Dietrich J, Lasco TM, et al. (2010) Non-clinical efficacy and safety of HyVac4:IC31 vaccine administered in a BCG prime-boost regimen. Vaccine. 28: 1084-93
Yamamoto T, Lasco TM, Uchida K, et al. (2007) Mycobacterium bovis BCG vaccination modulates TNF-alpha production after pulmonary challenge with virulent Mycobacterium tuberculosis in guinea pigs. Tuberculosis (Edinburgh, Scotland). 87: 155-65
Jeevan A, McFarland CT, Yoshimura T, et al. (2006) Production and characterization of guinea pig recombinant gamma interferon and its effect on macrophage activation Infection and Immunity. 74: 213-224
McMurray DN, Allen SS, Jeevan A, et al. (2005) Vaccine-induced cytokine responses in a guinea pig model of pulmonary tuberculosis Tuberculosis. 85: 295-301
Lasco TM, Cassone L, Kamohara H, et al. (2005) Evaluating the role of tumor necrosis factor-alpha in experimental pulmonary tuberculosis in the guinea pig. Tuberculosis (Edinburgh, Scotland). 85: 245-58
Cho H, Lasco TM, Allen SS, et al. (2005) Recombinant guinea pig tumor necrosis factor alpha stimulates the expression of interleukin-12 and the inhibition of Mycobacterium tuberculosis growth in macrophages. Infection and Immunity. 73: 1367-76
Izzo A, Brandt L, Lasco T, et al. (2005) NIH pre-clinical screening program: overview and current status. Tuberculosis (Edinburgh, Scotland). 85: 25-8
Brandt L, Skeiky YA, Alderson MR, et al. (2004) The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs. Infection and Immunity. 72: 6622-32
Allen SS, Cassone L, Lasco TM, et al. (2004) Effect of neutralizing transforming growth factor beta1 on the immune response against Mycobacterium tuberculosis in guinea pigs. Infection and Immunity. 72: 1358-63
Lasco TM, Turner OC, Cassone L, et al. (2004) Rapid accumulation of eosinophils in lung lesions in guinea pigs infected with Mycobacterium tuberculosis. Infection and Immunity. 72: 1147-9
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