Kareem N. Mohni, Ph.D.
Affiliations: | 2012 | Molecular Microbiology and Structural Biology | University of Connecticut, Storrs, CT, United States |
Area:
Virology Biology, Cell BiologyGoogle:
"Kareem Mohni"Parents
Sign in to add mentor| Sandra K. Weller | grad student | 2012 | University of Connecticut | |
| (Herpes Simplex Virus type 1 disables cellular ATR-mediated DNA damage signaling.) | ||||
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Publications
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| Wessel SR, Mohni KN, Luzwick JW, et al. (2019) Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Reports. 28: 3497-3509.e4 |
| Thompson PS, Amidon KM, Mohni KN, et al. (2019) Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link. Nature Structural & Molecular Biology |
| Mohni KN, Wessel SR, Zhao R, et al. (2018) HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell |
| Lou DI, Kim ET, Meyerson NR, et al. (2016) An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host & Microbe. 20: 178-188 |
| Kavanaugh G, Ye F, Mohni KN, et al. (2015) A whole genome RNAi screen identifies replication stress response genes. Dna Repair. 35: 55-62 |
| Dungrawala H, Rose KL, Bhat KP, et al. (2015) The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability. Molecular Cell. 59: 998-1010 |
| Pozhidaeva AK, Mohni KN, Dhe-Paganon S, et al. (2015) Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1. The Journal of Biological Chemistry. 290: 22907-18 |
| Kavanaugh G, Zhao R, Guo Y, et al. (2015) Enhancer of Rudimentary Homolog affects the replication stress response through regulation of RNA processing. Molecular and Cellular Biology |
| Mohni KN, Thompson PS, Luzwick JW, et al. (2015) A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments. Plos One. 10: e0125482 |
| Smith S, Reuven N, Mohni KN, et al. (2014) Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response. Journal of Virology. 88: 10146-56 |