Jennifer A. Mertz, Ph.D.

Affiliations: 
2003 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology, Cell Biology
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"Jennifer Mertz"

Parents

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Jaquelin P. Dudley grad student 2003 UT Austin
 (Identification and characterization of the T-cell-specific enhancer of type B leukemogenic virus.)
BETA: Related publications

Publications

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Huang Y, Nahar S, Nakagawa A, et al. (2016) Regulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Ghosh S, Taylor A, Chin M, et al. (2016) Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition. The Journal of Biological Chemistry
Albrecht BK, Gehling VS, Hewitt MC, et al. (2016) Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials. Journal of Medicinal Chemistry
Conery AR, Centore RC, Spillane KL, et al. (2016) Preclinical anticancer efficacy of BET bromodomain inhibitors is determined by the apoptotic response. Cancer Research
Conery AR, Centore RC, Neiss A, et al. (2016) Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. Elife. 5
Taylor AM, Vaswani RG, Gehling VS, et al. (2016) Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains Acs Medicinal Chemistry Letters. 7: 145-150
Hewitt MC, Leblanc Y, Gehling VS, et al. (2015) Development of methyl isoxazoleazepines as inhibitors of BET. Bioorganic & Medicinal Chemistry Letters. 25: 1842-8
Gehling VS, Hewitt MC, Vaswani RG, et al. (2013) Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. Acs Medicinal Chemistry Letters. 4: 835-40
Mertz JA, Conery AR, Bryant BM, et al. (2011) Targeting MYC dependence in cancer by inhibiting BET bromodomains. Proceedings of the National Academy of Sciences of the United States of America. 108: 16669-74
Dudley JP, Mertz JA, Bhadra S, et al. (2011) Endogenous retroviruses and cancer Retroviruses and Insights Into Cancer. 119-162
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