Jeffrey R. Skaar, Ph.D.
Affiliations: | 2006 | Harvard University, Cambridge, MA, United States |
Area:
Molecular BiologyGoogle:
"Jeffrey Skaar"Parents
Sign in to add mentor| James A. DeCaprio | grad student | 2006 | Harvard | |
| (Biochemical and genetic characterization of cullin 7- and PARC-containing complexes.) | ||||
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Publications
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| Shi W, Vu T, Boucher D, et al. (2017) Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood |
| Dankert JF, Rona G, Clijsters L, et al. (2016) Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2. Molecular Cell |
| Skaar JR, Ferris AL, Wu X, et al. (2015) The Integrator complex controls the termination of transcription at diverse classes of gene targets. Cell Research. 25: 288-305 |
| Skaar JR, Pagan JK, Pagano M. (2014) SCF ubiquitin ligase-targeted therapies. Nature Reviews. Drug Discovery. 13: 889-903 |
| Skaar JR, Pagan JK, Pagano M. (2013) Mechanisms and function of substrate recruitment by F-box proteins. Nature Reviews. Molecular Cell Biology. 14: 369-81 |
| Silverman JS, Skaar JR, Pagano M. (2012) SCF ubiquitin ligases in the maintenance of genome stability. Trends in Biochemical Sciences. 37: 66-73 |
| Duan S, Skaar JR, Kuchay S, et al. (2011) mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. Molecular Cell. 44: 317-24 |
| Peschiaroli A, Skaar JR, Pagano M, et al. (2010) The ubiquitin-specific protease USP47 is a novel Β-TRCP interactor regulating cell survival Oncogene. 29: 1384-1393 |
| Skaar JR, Richard DJ, Saraf A, et al. (2009) INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology. 187: 25-32 |
| Skaar JR, Pagano M. (2009) Control of cell growth by the SCF and APC/C ubiquitin ligases. Current Opinion in Cell Biology. 21: 816-24 |