Kwun W. Wen, Ph.D.

Affiliations: 
2010 Microbiology & Immunology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Virology Biology, Microbiology Biology, Immunology
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"Kwun Wen"

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Blossom Damania grad student 2010 UNC Chapel Hill
 (Characterization of the K1 protein of Kaposi sarcoma-associated herpesvirus and development of a novel vaccine for protection against rhadinovirus infection.)
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Publications

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Wen KW, Wang L, Menke JR, et al. (2021) Cancers associated with human gammaherpesviruses. The Febs Journal
Wen KW, Fakhri B, Menke J, et al. (2020) Complexities in the diagnosis of large B-cell lymphomas, classic Hodgkin lymphomas and overlapping peripheral T-cell lymphomas simplified: An evidence-based guide. Annals of Diagnostic Pathology. 46: 151534
Wen KW, Rabinovitch PS, Wang D, et al. (2020) Utility of DNA flow cytometry in distinguishing between malignant and benign intrahepatic biliary lesions. Virchows Archiv : An International Journal of Pathology
Abrahams CL, Li X, Embry M, et al. (2018) Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001. Oncotarget. 9: 37700-37714
Embry M, Li X, Yu A, et al. (2017) CD74 Is Expressed in Relapsed and Refractory Multiple Myeloma and Can be Targeted with a Novel Anti-CD74 Antibody Drug Conjugate, SΤRO-001 Blood. 130: 4420-4420
Chen W, Sin SH, Wen KW, et al. (2012) Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. Plos Pathogens. 8: e1003048
Lei Y, Wen H, Yu Y, et al. (2012) The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 36: 933-46
Wen KW, Damania B. (2010) Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1. Oncogene. 29: 3532-44
Wen KW, Damania B. (2010) Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Letters. 289: 140-50
Wen KW, Dittmer DP, Damania B. (2009) Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus. Journal of Virology. 83: 9786-802
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