Matthew T. Murrell, Ph.D.

Affiliations: 
2004 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology
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"Matthew Murrell"

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Anne Moscona grad student 2004 Mount Sinai School of Medicine
 (Paramyxovirus sensitivity to receptor binding and neuraminidase inhibition.)
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Publications

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Porotto M, Fornabaio M, Greengard O, et al. (2006) Paramyxovirus receptor-binding molecules: Engagement of one site on the hemagglutinin-neuraminidase protein modulates activity at the second site Journal of Virology. 80: 1204-1213
Porotto M, Murrell M, Greengard O, et al. (2005) Influence of the human parainfluenza virus 3 attachment protein's neuraminidase activity on its capacity to activate the fusion protein Journal of Virology. 79: 2383-2392
Porotto M, Murrell M, Greengard O, et al. (2004) Inhibition of parainfluenza virus type 3 and newcastle disease virus hemagglutinin-neuraminidase receptor binding: Effect of receptor avidity and steric hindrance at the inhibitor binding sites Journal of Virology. 78: 13911-13919
Porotto M, Murrell M, Greengard O, et al. (2003) Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: An HN mutation diminishes the rate of F activation and fusion Journal of Virology. 77: 3647-3654
Murrell M, Porotto M, Weber T, et al. (2003) Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir) Journal of Virology. 77: 309-317
Murrell MT, Porotto M, Greengard O, et al. (2001) A single amino acid alteration in the human parainfluenza virus type 3 hemagglutinin-neuraminidase glycoprotein confers resistance to the inhibitory effects of zanamivir on receptor binding and neuraminidase activity Journal of Virology. 75: 6310-6320
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