Eva Sahakian, Ph.D.

Affiliations: 
2010 Loma Linda University, Loma Linda, United States 
Area:
Microbiology Biology, Genetics, Molecular Biology
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"Eva Sahakian"

Parents

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Carlos A. Casiano grad student Loma Linda University
Michael B. Lilly grad student 2010 Loma Linda University
 (Regulation of PIM1 under hypoxia in prostate cancer.)
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Publications

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Lienlaf M, Perez-Villarroel P, Knox T, et al. (2016) Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Molecular Oncology
Villagra A, Sahakian E, Seto E. (2016) Preparation and Biochemical Analysis of Classical Histone Deacetylases Methods in Enzymology
Woan KV, Lienlaf M, Perez-Villaroel P, et al. (2015) Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation. Molecular Oncology
Sahakian E, Powers JJ, Chen J, et al. (2015) Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function. Molecular Immunology. 63: 579-85
Cheng F, Lienlaf M, Wang HW, et al. (2014) A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 193: 2850-62
Chavez JC, Sahakian E, Pinilla-Ibarz J. (2013) Ibrutinib: an evidence-based review of its potential in the treatment of advanced chronic lymphocytic leukemia. Core Evidence. 8: 37-45
Sahakian E, Woan K, Villagra A, et al. (2013) Epigenetic Approaches: Emerging Role of Histone Deacetylase Inhibitors in Cancer Immunotherapy Cancer Immunotherapy: Immune Suppression and Tumor Growth: Second Edition. 353-372
Cheng F, Wang H, Horna P, et al. (2012) Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity. Cancer Research. 72: 4440-8
Woan KV, Sahakian E, Sotomayor EM, et al. (2012) Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer. Immunology and Cell Biology. 90: 55-65
Wang H, Cheng F, Woan K, et al. (2011) Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10. Journal of Immunology (Baltimore, Md. : 1950). 186: 3986-96
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