Rafael E. Luna, Ph.D.

Affiliations: 
2004 Louisiana State University, Baton Rouge, LA, United States 
Area:
Microbiology Biology
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"Rafael Luna"

Parents

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Konstantin G. Kousoulas grad student 2004 Louisiana State
 (Molecular genetics and functions of Kaposi's sarcoma associated herpesvirus glycoproteins in virus entry, egress and virus-induced cell fusion.)
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Publications

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Kozel C, Thompson B, Hustak S, et al. (2016) Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation. Nucleic Acids Research
Papadopoulos E, Jenni S, Kabha E, et al. (2014) Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G. Proceedings of the National Academy of Sciences of the United States of America. 111: E3187-95
Martin-Marcos P, Nanda JS, Luna RE, et al. (2014) Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. Rna (New York, N.Y.). 20: 150-67
Luna RE, Arthanari H, Hiraishi H, et al. (2013) The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes. Biochemistry. 52: 9510-8
Martin-Marcos P, Nanda J, Luna RE, et al. (2013) β-Hairpin loop of eukaryotic initiation factor 1 (eIF1) mediates 40 S ribosome binding to regulate initiator tRNA(Met) recruitment and accuracy of AUG selection in vivo. The Journal of Biological Chemistry. 288: 27546-62
Luna RE, Arthanari H, Hiraishi H, et al. (2012) The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β. Cell Reports. 1: 689-702
Milbradt AG, Kulkarni M, Yi T, et al. (2011) Structure of the VP16 transactivator target in the Mediator. Nature Structural & Molecular Biology. 18: 410-5
Reibarkh M, Yamamoto Y, Singh CR, et al. (2008) Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection. The Journal of Biological Chemistry. 283: 1094-103
Melancon JM, Luna RE, Foster TP, et al. (2005) Herpes simplex virus type 1 gK is required for gB-mediated virus-induced cell fusion, while neither gB and gK nor gB and UL20p function redundantly in virion de-envelopment. Journal of Virology. 79: 299-313
Luna RE, Zhou F, Baghian A, et al. (2004) Kaposi's sarcoma-associated herpesvirus glycoprotein K8.1 is dispensable for virus entry. Journal of Virology. 78: 6389-98
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