Jeffrey M. Melancon, Ph.D.

Affiliations: 
2004 Louisiana State University, Baton Rouge, LA, United States 
Area:
Microbiology Biology
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"Jeffrey Melancon"

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Konstantin G. Kousoulas grad student 2004 Louisiana State
 (Genetics and functions of herpes simplex virus type 1 membrane proteins in virus-induced cell fusion, virion morphogenesis and egress.)
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Publications

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Melancon JM, Fulmer PA, Kousoulas KG. (2007) The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment. Virology Journal. 4: 120
Israyelyan AH, Melancon JM, Lomax LG, et al. (2007) Effective treatment of human breast tumor in a mouse xenograft model with herpes simplex virus type 1 specifying the NV1020 genomic deletion and the gBsyn3 syncytial mutation enabling high viral replication and spread in breast cancer cells. Human Gene Therapy. 18: 457-73
Fulmer PA, Melancon JM, Baines JD, et al. (2007) UL20 protein functions precede and are required for the UL11 functions of herpes simplex virus type 1 cytoplasmic virion envelopment. Journal of Virology. 81: 3097-108
Petit CM, Melancon JM, Chouljenko VN, et al. (2005) Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion. Virology. 341: 215-30
Melancon JM, Luna RE, Foster TP, et al. (2005) Herpes simplex virus type 1 gK is required for gB-mediated virus-induced cell fusion, while neither gB and gK nor gB and UL20p function redundantly in virion de-envelopment. Journal of Virology. 79: 299-313
Foster TP, Melancon JM, Olivier TL, et al. (2004) Herpes simplex virus type 1 glycoprotein K and the UL20 protein are interdependent for intracellular trafficking and trans-Golgi network localization. Journal of Virology. 78: 13262-77
Melancon JM, Foster TP, Kousoulas KG. (2004) Genetic analysis of the herpes simplex virus type 1 UL20 protein domains involved in cytoplasmic virion envelopment and virus-induced cell fusion. Journal of Virology. 78: 7329-43
Foster TP, Melancon JM, Baines JD, et al. (2004) The herpes simplex virus type 1 UL20 protein modulates membrane fusion events during cytoplasmic virion morphogenesis and virus-induced cell fusion. Journal of Virology. 78: 5347-57
Foster TP, Melancon JM, Kousoulas KG. (2001) An alpha-helical domain within the carboxyl terminus of herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) is associated with cell fusion and resistance to heparin inhibition of cell fusion. Virology. 287: 18-29
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