George R. Gunn, Ph.D.

Affiliations: 
2001 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"George Gunn"

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Yvonne Paterson grad student 2001 Penn
 (Recombinant Listeria monocytogenes as a tumor therapeutic.)
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Publications

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Gupta S, Devanarayan V, Finco D, et al. (2011) Recommendations for the validation of cell-based assays used for the detection of neutralizing antibody immune responses elicited against biological therapeutics. Journal of Pharmaceutical and Biomedical Analysis. 55: 878-88
Finco D, Baltrukonis D, Clements-Egan A, et al. (2011) Comparison of competitive ligand-binding assay and bioassay formats for the measurement of neutralizing antibodies to protein therapeutics. Journal of Pharmaceutical and Biomedical Analysis. 54: 351-8
Wu BW, Gunn GR, Shankar G. (2011) Competitive Ligand-Binding Assays for the Detection of Neutralizing Antibodies Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations. 175-192
Shi FF, Gunn GR, Snyder LA, et al. (2007) Intradermal vaccination of MUC1 transgenic mice with MUC1/IL-18 plasmid DNA suppresses experimental pulmonary metastases. Vaccine. 25: 3338-46
Swencki-Underwood B, Cunningham MR, Heavner GA, et al. (2006) Engineering human IL-18 with increased bioactivity and bioavailability. Cytokine. 34: 114-24
Snyder LA, Goletz TJ, Gunn GR, et al. (2006) A MUC1/IL-18 DNA vaccine induces anti-tumor immunity and increased survival in MUC1 transgenic mice. Vaccine. 24: 3340-52
Sewell DA, Shahabi V, Gunn GR, et al. (2004) Recombinant Listeria vaccines containing PEST sequences are potent immune adjuvants for the tumor-associated antigen human papillomavirus-16 E7. Cancer Research. 64: 8821-5
Gunn GR, Zubair A, Peters C, et al. (2001) Two Listeria monocytogenes vaccine vectors that express different molecular forms of human papilloma virus-16 (HPV-16) E7 induce qualitatively different T cell immunity that correlates with their ability to induce regression of established tumors immortalized by HPV-16. Journal of Immunology (Baltimore, Md. : 1950). 167: 6471-9
Gunn GR, Peters C, Paterson Y. (2001) Listeriolysin--a useful cytolysin. Trends in Microbiology. 9: 161-2
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