Spencer C. Liang, Ph.D.

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Cell Biology, Microbiology Biology
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"Spencer Liang"

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Arlene H. Sharpe grad student 2005 Harvard
 (Elucidating the roles of PD-L1 and PD-L2 costimulation on T cell activation, differentiation and effector function.)
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Publications

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Liang SC, Moskalenko M, Van Roey M, et al. (2013) Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy. Clinical Immunology (Orlando, Fla.). 148: 287-98
Liang SC, Nickerson-Nutter C, Pittman DD, et al. (2010) IL-22 induces an acute-phase response. Journal of Immunology (Baltimore, Md. : 1950). 185: 5531-8
Keir ME, Liang SC, Guleria I, et al. (2006) Tissue expression of PD-L1 mediates peripheral T cell tolerance. The Journal of Experimental Medicine. 203: 883-95
Liang SC, Greenwald RJ, Latchman YE, et al. (2006) PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis. European Journal of Immunology. 36: 58-64
Latchman YE, Liang SC, Wu Y, et al. (2004) PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 10691-6
Rodig N, Ryan T, Allen JA, et al. (2003) Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis. European Journal of Immunology. 33: 3117-26
Liang SC, Latchman YE, Buhlmann JE, et al. (2003) Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses. European Journal of Immunology. 33: 2706-16
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