Edward J. Brignole, Ph.D.
Affiliations: | 2005 | Johns Hopkins University, Baltimore, MD |
Area:
Microbiology Biology, Molecular Biology, BiochemistryGoogle:
"Edward Brignole"Parents
Sign in to add mentor| Wade Gibson | grad student | 2005 | Johns Hopkins | |
| (Expression and purification of the human cytomegalovirus protease precursor: Initial characterizations of its physical and enzymatic properties.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Rogala KB, Gu X, Kedir JF, et al. (2019) Structural basis for the docking of mTORC1 on the lysosomal surface. Science (New York, N.Y.) |
| Chen PY, Funk MA, Brignole EJ, et al. (2018) Disruption of an oligomeric interface prevents allosteric inhibition of class Ia ribonucleotide reductase. The Journal of Biological Chemistry |
| Shen K, Huang RK, Brignole EJ, et al. (2018) Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Nature |
| Brignole EJ, Tsai KL, Chittuluru J, et al. (2018) 3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife. 7 |
| Cory SA, Van Vranken JG, Brignole EJ, et al. (2017) Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. Proceedings of the National Academy of Sciences of the United States of America |
| Ando N, Li H, Brignole EJ, et al. (2016) Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer. Biochemistry |
| Mattaini KR, Brignole EJ, Kini M, et al. (2015) An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation. Cancer & Metabolism. 3: 5 |
| Minnihan EC, Ando N, Brignole EJ, et al. (2013) Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase. Proceedings of the National Academy of Sciences of the United States of America. 110: 3835-40 |
| Aye Y, Brignole EJ, Long MJ, et al. (2012) Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers. Chemistry & Biology. 19: 799-805 |
| Brignole EJ, Ando N, Zimanyi CM, et al. (2012) The prototypic class Ia ribonucleotide reductase from Escherichia coli: still surprising after all these years. Biochemical Society Transactions. 40: 523-30 |