Thomas M. McCaughtry, Ph.D.

Affiliations: 
2008 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Cell Biology
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"Thomas McCaughtry"

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Kristin A. Hogquist grad student 2008 UMN
 (T cell development: The generation of functional and self-tolerant T cells via positive selection and negative selection, and their export for immunological surveillance.)
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Publications

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Gallagher S, Yusuf I, McCaughtry TM, et al. (2015) MEDI-551 Treatment Effectively Depletes B Cells and Reduces Serum Titers of Autoantibodies in Sle1-Human CD19 Transgenic Mice. Arthritis & Rheumatology (Hoboken, N.J.)
Yusuf I, Stern J, McCaughtry TM, et al. (2014) Germinal center B cell depletion diminishes CD4+ follicular T helper cells in autoimmune mice. Plos One. 9: e102791
Tai X, Erman B, Alag A, et al. (2013) Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals. Immunity. 38: 1116-28
McCaughtry T, Yusuf I, Gallagher S, et al. (2013) 178 Cytokine. 63: 285
McCaughtry TM, Etzensperger R, Alag A, et al. (2012) Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus Journal of Experimental Medicine. 209: 2263-2276
Adoro S, McCaughtry T, Erman B, et al. (2012) Coreceptor gene imprinting governs thymocyte lineage fate. The Embo Journal. 31: 366-77
McCaughtry TM, Hogquist KA. (2008) Central tolerance: what have we learned from mice? Seminars in Immunopathology. 30: 399-409
McCaughtry TM, Baldwin TA, Wilken MS, et al. (2008) Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla. The Journal of Experimental Medicine. 205: 2575-84
McCaughtry TM, Wilken MS, Hogquist KA. (2007) Thymic emigration revisited. The Journal of Experimental Medicine. 204: 2513-20
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