Walter A. Scott

Affiliations: 
University of Miami, Coral Gables, FL 
Area:
Biochemistry, Microbiology Biology
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"Walter Scott"
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Publications

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Lu G, Matsuura SE, Barrientos A, et al. (2013) HIV-1 infection is blocked at an early stage in cells devoid of mitochondrial DNA. Plos One. 8: e78035
Lu G, Acosta-Hoyos AJ, Scott WA. (2013) Nucleoside RT inhibitors: Structural and molecular biology Human Immunodeficiency Virus Reverse Transcriptase: a Bench-to-Bedside Success. 99-122
Acosta-Hoyos AJ, Matsuura SE, Meyer PR, et al. (2012) A role of template cleavage in reduced excision of chain-terminating nucleotides by human immunodeficiency virus type 1 reverse transcriptase containing the M184V mutation. Journal of Virology. 86: 5122-33
Scott WA. (2011) Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistance. Viruses. 3: 20-5
Acosta-Hoyos AJ, Scott WA. (2010) The Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance. Viruses. 2: 372-394
Rutvisuttinunt W, Meyer PR, Scott WA. (2008) Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template. Plos One. 3: e3561
Meyer PR, Rutvisuttinunt W, Matsuura SE, et al. (2007) Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnet. Journal of Molecular Biology. 369: 41-54
Meyer PR, Smith AJ, Matsuura SE, et al. (2006) Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants. Antimicrobial Agents and Chemotherapy. 50: 3607-14
Smith AJ, Scott WA. (2006) The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell. Current Pharmaceutical Design. 12: 1827-41
Smith AJ, Meyer PR, Asthana D, et al. (2005) Intracellular substrates for the primer-unblocking reaction by human immunodeficiency virus type 1 reverse transcriptase: detection and quantitation in extracts from quiescent- and activated-lymphocyte subpopulations. Antimicrobial Agents and Chemotherapy. 49: 1761-9
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