Joshua J. Obar, Ph.D.

Affiliations: 
2006 Dartmouth College, Hanover, NH, United States 
Area:
Immunology, Microbiology Biology, Virology Biology
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"Joshua Obar"

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Edward J. Usherwood grad student 2006 Dartmouth
 (CD8 T cell responses to murine gamma-herpesvirus 68: Viral persistence shapes the immune response.)
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Publications

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Plumlee CR, Obar JJ, Colpitts SL, et al. (2015) Early Effector CD8 T Cells Display Plasticity in Populating the Short-Lived Effector and Memory-Precursor Pools Following Bacterial or Viral Infection. Scientific Reports. 5: 12264
Graham AC, Temple RM, Obar JJ. (2015) Mast cells and influenza a virus: association with allergic responses and beyond. Frontiers in Immunology. 6: 238
Caffrey AK, Lehmann MM, Zickovich JM, et al. (2015) IL-1α signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge. Plos Pathogens. 11: e1004625
Shepardson KM, Jhingran A, Caffrey A, et al. (2014) Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection. Plos Pathogens. 10: e1004378
Graham AC, Hilmer KM, Zickovich JM, et al. (2013) Inflammatory response of mast cells during influenza A virus infection is mediated by active infection and RIG-I signaling. Journal of Immunology (Baltimore, Md. : 1950). 190: 4676-84
Xu D, Fu HH, Obar JJ, et al. (2013) A potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infection. Plos One. 8: e56539
Colpitts SL, Stoklasek TA, Plumlee CR, et al. (2012) Cutting edge: The role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo Journal of Immunology. 188: 2483-2487
Obar JJ, Molloy MJ, Jellison ER, et al. (2010) CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses. Proceedings of the National Academy of Sciences of the United States of America. 107: 193-8
Fuse S, Obar JJ, Bellfy S, et al. (2006) CD80 and CD86 control antiviral CD8+ T-cell function and immune surveillance of murine gammaherpesvirus 68. Journal of Virology. 80: 9159-70
Obar JJ, Fuse S, Leung EK, et al. (2006) Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. Journal of Virology. 80: 8303-15
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