Geoffrey H. Holm, Ph.D.

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
Area:
Microbiology Biology, Immunology
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"Geoffrey Holm"

Parents

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Dana Gabuzda grad student 2004 Harvard
 (Mechanisms of bystander T cell apoptosis in HIV-1 infection.)
Terence S. Dermody post-doc 2005-2008 Vanderbilt
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Publications

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Doms A, Sanabria T, Hansen JN, et al. (2018) 25-hydroxycholesterol Production by Interferon Stimulated Gene Cholesterol-25-hydroxylase Restricts Mammalian Reovirus Infection. Journal of Virology
Stuart JD, Holm GH, Boehme KW. (2018) Differential delivery of genomic dsRNA causes reovirus strain-specific differences in IRF3 activation. Journal of Virology
Danthi P, Holm GH, Stehle T, et al. (2013) Reovirus receptors, cell entry, and proapoptotic signaling. Advances in Experimental Medicine and Biology. 790: 42-71
Anafu AA, Bowen CH, Chin CR, et al. (2013) Interferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry. The Journal of Biological Chemistry. 288: 17261-71
Knowlton JJ, Dermody TS, Holm GH. (2012) Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-κB-dependent expression of Noxa. Journal of Virology. 86: 1650-60
Danthi P, Pruijssers AJ, Berger AK, et al. (2010) Bid regulates the pathogenesis of neurotropic reovirus. Plos Pathogens. 6: e1000980
Holm GH, Pruijssers AJ, Li L, et al. (2010) Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance. Journal of Virology. 84: 6900-8
Zurney J, Kobayashi T, Holm GH, et al. (2009) Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9. Journal of Virology. 83: 2178-87
Danthi P, Kobayashi T, Holm GH, et al. (2008) Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency. Journal of Virology. 82: 161-72
Sherry B, Zurney J, Kobayashi T, et al. (2008) 237 Reovirus inhibits interferon signaling through a novel mechanism involving nuclear accumulation of IRF9 Cytokine. 43: 296
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