Sean M. Armour, Ph.D.
Affiliations: | 2010 | Harvard University, Cambridge, MA, United States |
Area:
Molecular BiologyGoogle:
"Sean Armour"Parents
Sign in to add mentor| David Sinclair | grad student | 2010 | Harvard | |
| (Characterization of mammalian sirtuin regulators, targets, and complexes.) | ||||
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Publications
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| Armour SM, Remsberg JR, Damle M, et al. (2017) An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides. Nature Communications. 8: 549 |
| Zhang Y, Fang B, Emmett MJ, et al. (2015) GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock. Science (New York, N.Y.). 348: 1488-92 |
| Fang B, Everett LJ, Jager J, et al. (2014) Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo. Cell. 159: 1140-52 |
| Hubbard BP, Loh C, Gomes AP, et al. (2013) Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism. Cell Cycle (Georgetown, Tex.). 12: 2233-40 |
| Hubbard BP, Gomes AP, Dai H, et al. (2013) Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (New York, N.Y.). 339: 1216-9 |
| Armour SM, Bennett EJ, Braun CR, et al. (2013) A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. Molecular and Cellular Biology. 33: 1487-502 |
| Beirowski B, Gustin J, Armour SM, et al. (2011) Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: E952-61 |
| Bernier M, Paul RK, Martin-Montalvo A, et al. (2011) Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein. The Journal of Biological Chemistry. 286: 19270-9 |
| Armour SM, Baur JA, Hsieh SN, et al. (2009) Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. Aging. 1: 515-28 |
| Kim D, Nguyen MD, Dobbin MM, et al. (2007) SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. The Embo Journal. 26: 3169-79 |