Joshua A. Blodgett, Ph.D.

2007 Microbiology University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2007-2012 Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
 2012-2014 Warp Drive Bio 
 2014- Biology Washington University, Saint Louis, St. Louis, MO 
Actinomycete Microbiology, Natural Products Chemistry
"Joshua Blodgett"


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William W. Metcalf grad student 2007 UIUC
 (Genetic and biochemical analysis of phosphinothricin tripeptide biosynthesis in Streptomyces viridochromogenes.)
Jon C. Clardy post-doc 2007-2012 Harvard Medical School (Chemistry Tree)


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Chris Harper grad student 2020- Washington University
Yunci Qi grad student 2015-2021 Washington University
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Ko B, D'Alessandro J, Douangkeomany L, et al. (2019) Construction of a new integrating vector from actinophage ϕOZJ and its use in multiplex Streptomyces transformation. Journal of Industrial Microbiology & Biotechnology
Qi Y, Ding E, Blodgett J. (2017) Native and engineered clifednamide biosynthesis in multiple Streptomyces spp. Acs Synthetic Biology
Blodgett JA, Zhang JK, Yu X, et al. (2015) Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products. The Journal of Antibiotics
Book AJ, Lewin GR, McDonald BR, et al. (2014) Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose. Applied and Environmental Microbiology. 80: 4692-701
Cao S, Blodgett JA, Clardy J. (2010) Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain. Organic Letters. 12: 4652-4
Blodgett JA, Oh DC, Cao S, et al. (2010) Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria. Proceedings of the National Academy of Sciences of the United States of America. 107: 11692-7
Seyedsayamdost MR, Chandler JR, Blodgett JA, et al. (2010) Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Organic Letters. 12: 716-9
Shao Z, Blodgett JA, Circello BT, et al. (2008) Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways. The Journal of Biological Chemistry. 283: 23161-8
Blodgett JA, Thomas PM, Li G, et al. (2007) Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nature Chemical Biology. 3: 480-5
Woodyer RD, Shao Z, Thomas PM, et al. (2006) Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. Chemistry & Biology. 13: 1171-82
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