Timothy J. LaRocca, Ph.D.

Affiliations: 
2009 Stony Brook University, Stony Brook, NY, United States 
Area:
Microbiology Biology, Immunology
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"Timothy LaRocca"

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Jorge L. Benach grad student 2009 SUNY Stony Brook
 (The mechanism of complement-independent bactericidal antibodies against Borrelia.)
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Publications

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LaRocca TJ, Sosunov SA, Shakerley NL, et al. (2016) Hyperglycemic conditions prime cells for RIP1-dependent necroptosis. The Journal of Biological Chemistry
LaRocca TJ, Stivison EA, Hod EA, et al. (2014) Human-specific bacterial pore-forming toxins induce programmed necrosis in erythrocytes. Mbio. 5: e01251-14
Toledo A, Crowley JT, Coleman JL, et al. (2014) Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi. Mbio. 5: e00899-14
Randis TM, Zaklama J, LaRocca TJ, et al. (2013) Vaginolysin drives epithelial ultrastructural responses to Gardnerella vaginalis. Infection and Immunity. 81: 4544-50
LaRocca TJ, Pathak P, Chiantia S, et al. (2013) Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts. Plos Pathogens. 9: e1003353
Crowley JT, Toledo AM, LaRocca TJ, et al. (2013) Lipid exchange between Borrelia burgdorferi and host cells. Plos Pathogens. 9: e1003109
LaRocca TJ, Crowley JT, Cusack BJ, et al. (2010) Cholesterol lipids of Borrelia burgdorferi form lipid rafts and are required for the bactericidal activity of a complement-independent antibody. Cell Host & Microbe. 8: 331-42
LaRocca TJ, Holthausen DJ, Hsieh C, et al. (2009) The bactericidal effect of a complement-independent antibody is osmolytic and specific to Borrelia. Proceedings of the National Academy of Sciences of the United States of America. 106: 10752-7
LaRocca TJ, Katona LI, Thanassi DG, et al. (2008) Bactericidal action of a complement-independent antibody against relapsing fever Borrelia resides in its variable region. Journal of Immunology (Baltimore, Md. : 1950). 180: 6222-8
LaRocca TJ, Benach JL. (2008) The important and diverse roles of antibodies in the host response to Borrelia infections. Current Topics in Microbiology and Immunology. 319: 63-103
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