Margaret J. Lange, Ph.D.

Affiliations: 
2008 Molecular Microbiology and Immunology University of Missouri - Columbia, Columbia, MO, United States 
Area:
Immunology
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"Margaret Lange"

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Michael L. Misfeldt grad student 2008 University of Missouri - Columbia
 (Hormonal regulation of the innate immune response and Toll-like receptors in the human endometrium.)
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Publications

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Song Z, Gremminger T, Singh G, et al. (2021) The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity. Nucleic Acids Research
Nguyen PDM, Zheng J, Gremminger TJ, et al. (2020) Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase. Nucleic Acids Research
Lange MJ, Lyddon TD, Johnson MC. (2019) Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses. Scientific Reports. 9: 8985
Lange MJ, Burke DH, Chaput JC. (2018) Activation of Innate Immune Responses by a Cytosine-Phosphate-Guanine Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid. Nucleic Acid Therapeutics
Alam KK, Chang JL, Lange MJ, et al. (2018) Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers. Molecular Therapy. Nucleic Acids. 13: 605-619
Porciani D, Cardwell LN, Tawiah KD, et al. (2018) Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications. 9: 2283
Lange MJ, Nguyen PD, Callaway MK, et al. (2017) RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers. Nucleic Acids Research
Camargo C, Lange MJ, Hill KJ, et al. (2015) 538. Promoter Compatibility Enables Viral Vectors to Deliver Antiviral RNA Genes Molecular Therapy. 23: S216
Hill KJ, Lange MJ, Burke DH. (2015) 141. Combinatorial Aptamer Transcripts (CATs) for HIV RT Suppression Molecular Therapy. 23: S57
Hill KJ, Swain AD, Lange MJ, et al. (2015) 137. Viral Hitchhiking to Increase Therapeutic Potential: Autonomously Packaged Elements (APEs) Molecular Therapy. 23: S56
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