William M. Shafer
Affiliations: | Biological and Biomedical Sciences | Emory University, Atlanta, GA |
Area:
Microbiology BiologyGoogle:
"William Shafer"Children
Sign in to add trainee| Wendy L. Veal | grad student | 2002 | Emory |
| Nazia Kamal | grad student | 2009 | Emory |
| Brea D. Duval | grad student | 2010 | Emory |
| Alexandra M. Mercante | grad student | 2011 | Emory |
| Elizabeth A. Ohneck | grad student | 2013 | Emory |
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Publications
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| Golparian D, Jacobsson S, Holley CL, et al. (2023) High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy |
| Lyu M, Ayala JC, Chirakos I, et al. (2022) Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump. Microbiology Spectrum. e0299022 |
| Edwards JL, Balthazar JT, Esposito DLA, et al. (2022) Potent and Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A. Msphere. e0036222 |
| Ayala JC, Balthazar JT, Shafer WM. (2022) Transcriptional regulation of the efflux pump operon: importance for antimicrobial resistance. Microbiology (Reading, England). 168 |
| Holley CL, Dhulipala V, Balthazar JT, et al. (2022) A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in . Antimicrobial Agents and Chemotherapy. 66: e0025122 |
| Ayala JC, Schmerer MW, Kersh EN, et al. (2022) Gonococcal Clinical Strains Bearing a Common Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene Frequently Possess a Promoter Mutation That Decreases Antibiotic Susceptibility. Mbio. e0027622 |
| Beggs GA, Ayala JC, Kavanaugh LG, et al. (2021) Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. Nucleic Acids Research |
| Ferreyra C, Osborn J, Moussy F, et al. (2020) Developing target product profiles for Neisseria gonorrhoeae diagnostics in the context of antimicrobial resistance: An expert consensus. Plos One. 15: e0237424 |
| Holley CL, Ayala JC, Shafer WM. (2020) Transcriptional control of the gonococcal ompA gene by the MisR/MisS two-component regulatory system. Scientific Reports. 10: 9425 |
| Lyu M, Moseng MA, Reimche JL, et al. (2020) Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance. Mbio. 11 |