Kathleen C. Prins, Ph.D.
Affiliations: | 2010 | Microbiology | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
Microbiology BiologyGoogle:
"Kathleen Prins"Parents
Sign in to add mentor| Christopher F. Basler | grad student | 2010 | Mount Sinai School of Medicine | |
| (Molecular basis for the IFN antagonist and viral polymerase cofactor functions of VP35, a critical Ebolavirus virulence factor.) | ||||
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| Leung DW, Prins KC, Basler CF, et al. (2010) Ebolavirus VP35 is a multifunctional virulence factor Virulence. 1: 526-531 |
| Prins KC, Binning JM, Shabman RS, et al. (2010) Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function Journal of Virology. 84: 10581-10591 |
| Leung DW, Borek D, Farahbakhsh M, et al. (2010) Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66: 689-692 |
| Leung DW, Shabman RS, Farahbakhsh M, et al. (2010) Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain Journal of Molecular Biology. 399: 347-357 |
| Leung DW, Prins KC, Borek DM, et al. (2010) Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 Nature Structural and Molecular Biology. 17: 165-172 |
| Prins KC, Delpeut S, Leung DW, et al. (2010) Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs Journal of Virology. 84: 3004-3015 |
| Prins KC, Cárdenas WB, Basler CF. (2009) Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. Journal of Virology. 83: 3069-77 |