David R. Friedmann, Ph.D.

2010 Molecular Genetics, Biochemistry, & Microbiology University of Cincinnati, Cincinnati, OH 
Molecular Biology, Biochemistry, General Biophysics
"David Friedmann"


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Rhett Kovall grad student 2010 University of Cincinnati
 (Thermodynamic and structural insights into CSL mediated transcription complexes.)
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Friedmann DR, Marmorstein R. (2013) Structure and mechanism of non-histone protein acetyltransferase enzymes. The Febs Journal. 280: 5570-81
Friedmann DR, Aguilar A, Fan J, et al. (2012) Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 19655-60
Yuan Z, Friedmann DR, VanderWielen BD, et al. (2012) Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2. The Journal of Biological Chemistry. 287: 34904-16
VanderWielen BD, Yuan Z, Friedmann DR, et al. (2011) Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes. The Journal of Biological Chemistry. 286: 14892-902
Conrady DG, Flagler MJ, Friedmann DR, et al. (2010) Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2. Plos One. 5: e15153
Friedmann DR, Kovall RA. (2010) Thermodynamic and structural insights into CSL-DNA complexes. Protein Science : a Publication of the Protein Society. 19: 34-46
Friedmann DR, Wilson JJ, Kovall RA. (2008) RAM-induced allostery facilitates assembly of a notch pathway active transcription complex. The Journal of Biological Chemistry. 283: 14781-91
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