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Alan N. Engelman

Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Virology Biology, Biochemistry, Microbiology Biology
"Alan N. Engelman"


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Naomi Rosenberg grad student 1990 Tufts
 (Isolation and characterization of Abelson murine leukemia virus mutants that are temperature-sensitive for transformation.)


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Richard W. Lu grad student 2005 Harvard
Kenneth A. Matreyek grad student 2013 Harvard
Ilker Oztop grad student 2014 Harvard
Gregory A. Sowd post-doc 2014-2016 Harvard (Crystallography Tree)
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Li M, Chen X, Wang H, et al. (2020) A peptide derived from lens epithelium-derived growth factor stimulates HIV-1 DNA integration and facilitates intasome structural studies. Journal of Molecular Biology
Cook NJ, Li W, Berta D, et al. (2020) Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science (New York, N.Y.)
Anderson-Daniels J, Singh PK, Sowd GA, et al. (2019) Dominant negative MA-CA fusion protein is incorporated into HIV-1 cores and inhibits nuclear entry of viral preintegration complexes. Journal of Virology
Jang S, Cook NJ, Pye VE, et al. (2019) Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6. Nucleic Acids Research
Achuthan V, Perreira JM, Sowd GA, et al. (2018) Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. Cell Host & Microbe
Engelman AN, Singh PK. (2018) Cellular and molecular mechanisms of HIV-1 integration targeting. Cellular and Molecular Life Sciences : Cmls. 75: 2491-2507
Zhu Y, Wang X, Forouzmand E, et al. (2018) Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation. Molecular Cell. 69: 62-74.e4
Sugimura R, Jha DK, Han A, et al. (2017) Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 545: 432-438
Lesbats P, Serrao E, Maskell DP, et al. (2017) Structural basis for spumavirus GAG tethering to chromatin. Proceedings of the National Academy of Sciences of the United States of America. 114: 5509-5514
Wang W, Zhou J, Halambage UD, et al. (2017) Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein. Journal of Virology. 91
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