Vitaly Polunovsky

Affiliations: 
Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Cell Biology, Oncology, Genetics
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"Vitaly Polunovsky"
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Publications

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Fagan DH, Fettig LM, Avdulov S, et al. (2017) Acquired Tamoxifen Resistance in MCF-7 Breast Cancer Cells Requires Hyperactivation of eIF4F-Mediated Translation. Hormones & Cancer
Bitterman PB, Polunovsky VA. (2015) eIF4E-mediated translational control of cancer incidence. Biochimica Et Biophysica Acta. 1849: 774-80
Issaenko OA, Bitterman PB, Polunovsky VA, et al. (2012) Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype. Cancer Gene Therapy. 19: 609-18
Jia Y, Polunovsky V, Bitterman PB, et al. (2012) Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target. Medicinal Research Reviews. 32: 786-814
Bitterman PB, Polunovsky VA. (2012) Translational control of cell fate: from integration of environmental signals to breaching anticancer defense. Cell Cycle (Georgetown, Tex.). 11: 1097-107
McCauley JA, Evenson K, Truitt M, et al. (2012) Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo Cancer Research. 72: 2347-2347
Jia Y, Chiu TL, Amin EA, et al. (2010) Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP. European Journal of Medicinal Chemistry. 45: 1304-13
Ghosh B, Benyumov AO, Ghosh P, et al. (2009) Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation. Acs Chemical Biology. 4: 367-77
Ghosh P, Cheng J, Chou TF, et al. (2008) Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein. Protein Expression and Purification. 60: 132-9
Larsson O, Li S, Issaenko OA, et al. (2007) Eukaryotic translation initiation factor 4E-induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors Cancer Research. 67: 6814-6824
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