Allison Fay, Ph.D.

Affiliations: 
2010 Columbia University, New York, NY 
Area:
Microbiology Biology
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"Allison Fay"

Parents

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Jonathan Dworkin grad student 2010 Columbia
 (Analysis of conserved proteins required for late stage peptidoglycan synthesis.)
Michael Glickman post-doc Weill Cornell Medical College
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Publications

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Xiao X, Fay A, Molina PS, et al. (2024) Structure of the M. tuberculosis DnaK-GrpE complex reveals how key DnaK roles are controlled. Nature Communications. 15: 660
Dupuy P, Ghosh S, Fay A, et al. (2023) Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis. Elife. 12
Warren GM, Ejaz A, Fay A, et al. (2023) Mycobacterial helicase Lhr abets resistance to DNA crosslinking agents mitomycin C and cisplatin. Nucleic Acids Research. 51: 218-235
Hosfelt J, Richards A, Zheng M, et al. (2021) An allosteric inhibitor of bacterial Hsp70 chaperone potentiates antibiotics and mitigates resistance. Cell Chemical Biology
Yin Y, Feng X, Yu H, et al. (2021) Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system. Cell Reports. 35: 109166
Fay A, Philip J, Saha P, et al. (2021) The DnaK Chaperone System Buffers the Fitness Cost of Antibiotic Resistance Mutations in Mycobacteria. Mbio. 12
Fay A, Czudnochowski N, Rock JM, et al. (2019) Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria. Mbio. 10
Ballinger E, Mosior J, Hartman T, et al. (2019) Opposing reactions in coenzyme A metabolism sensitize to enzyme inhibition. Science (New York, N.Y.). 363
Peek J, Lilic M, Montiel D, et al. (2018) Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nature Communications. 9: 4147
Lazar N, Fay A, Nandakumar M, et al. (2017) Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal. Molecular Microbiology
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