Jeanine F. Amacher, Ph.D.

Affiliations: 
2014 Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry, Cell Biology, General Chemistry
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"Jeanine Amacher"

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Dean R. Madden grad student 2014 Dartmouth
 (Understanding PDZ Affinity and Selectivity: All Residues Considered.)
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Publications

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Gao M, Mackley IGP, Mesbahi-Vasey S, et al. (2020) Structural Characterization and Computational Analysis of PDZ domains in Monosiga brevicollis. Protein Science : a Publication of the Protein Society
Amacher JF, Brooks L, Hampton TH, et al. (2020) Specificity in PDZ-peptide interaction networks: Computational analysis and review. Journal of Structural Biology: X. 4: 100022
Amacher JF, Zhong F, Lisi GP, et al. (2018) Correction to "A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch". Journal of the American Chemical Society
Amacher JF, Zhong F, Lisi GP, et al. (2015) A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch. Journal of the American Chemical Society
Qian Z, Xu X, Amacher JF, et al. (2015) Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity. Angewandte Chemie (International Ed. in English). 54: 5874-8
Amacher JF, Zhao R, Spaller MR, et al. (2014) Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain. Plos One. 9: e103650
Amacher JF, Cushing PR, Brooks L, et al. (2014) Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses. Structure (London, England : 1993). 22: 82-93
Amacher JF, Cushing PR, Bahl CD, et al. (2013) Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop. The Journal of Biological Chemistry. 288: 5114-26
Amacher JF, Cushing PR, Weiner JA, et al. (2011) Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 600-3
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