Jin-Hwan Han, Ph.D.

Affiliations: 
2009 Immunology Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Immunology
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"Jin-Hwan Han"

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Thereza Imanishi-Kari grad student 2009 Sackler School of Graduate Biomedical Sciences (Tufts University)
 (Activation of RNA-specific autoreactive B cells during B cell development on a normal and an autoimmune genetic background.)
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Publications

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Chen Y, Zhou S, Pradhan K, et al. (2023) Development and application of an in vitro assay to assess target-independent B-cell activation by targeted TLR7 immune agonists. Journal of Immunological Methods. 113553
Han JH, Cai M, Grein J, et al. (2020) Effective Anti-tumor Response by TIGIT Blockade Associated With FcγR Engagement and Myeloid Cell Activation. Frontiers in Immunology. 11: 573405
Thapa M, Tedesco D, Gumber S, et al. (2020) Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease. Journal of Immunology (Baltimore, Md. : 1950)
Wieland A, Kamphorst AO, Valanparambil RM, et al. (2018) Enhancing FcγR-mediated antibody effector function during persistent viral infection. Science Immunology. 3
McDonald G, Cabal N, Vannier A, et al. (2015) Female Bias in Systemic Lupus Erythematosus is Associated with the Differential Expression of X-Linked Toll-Like Receptor 8. Frontiers in Immunology. 6: 457
Thapa M, Chinnadurai R, Velazquez VM, et al. (2015) Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity. Hepatology (Baltimore, Md.). 61: 2067-79
Wieland A, Shashidharamurthy R, Kamphorst AO, et al. (2015) Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection. Immunity. 42: 367-78
Han JH, Umiker BR, Kazimirova AA, et al. (2014) Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression. European Journal of Immunology. 44: 215-26
Uebelhoer L, Han JH, Callendret B, et al. (2008) Stable cytotoxic T cell escape mutation in hepatitis C virus is linked to maintenance of viral fitness. Plos Pathogens. 4: e1000143
Han JH, Akira S, Calame K, et al. (2007) Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. Immunity. 27: 64-75
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