Kenneth A. Matreyek, Ph.D.

Affiliations: 
2013 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Virology Biology, Molecular Biology, Cell Biology
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"Kenneth Matreyek"

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Alan N. Engelman grad student 2013 Harvard
 (HIV-1 capsid engages nucleoporin NUP153 to promote viral nuclear entry.)
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Shukla N, Roelle SM, Suzart VG, et al. (2021) Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection. Plos Pathogens. 17: e1009715
Troyer Z, Alhusaini N, Tabler CO, et al. (2021) Extracellular vesicles carry SARS-CoV-2 spike protein and serve as decoys for neutralizing antibodies. Journal of Extracellular Vesicles. 10: e12112
Bruchez A, Sha K, Johnson J, et al. (2020) MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses. Science (New York, N.Y.)
Suiter CC, Moriyama T, Matreyek KA, et al. (2020) Massively parallel variant characterization identifies alleles associated with thiopurine toxicity. Proceedings of the National Academy of Sciences of the United States of America
Hasle N, Matreyek KA, Fowler DM. (2019) The Impact of Genetic Variants on Molecular Functions and Cellular Phenotypes. Cold Spring Harbor Perspectives in Medicine
Matreyek KA, Starita LM, Stephany JJ, et al. (2018) Multiplex assessment of protein variant abundance by massively parallel sequencing. Nature Genetics
Matreyek KA, Stephany JJ, Fowler DM. (2017) A platform for functional assessment of large variant libraries in mammalian cells. Nucleic Acids Research
Matreyek KA, Wang W, Serrao E, et al. (2014) Host and viral determinants for MxB restriction of HIV-1 infection. Retrovirology. 11: 90
Fribourgh JL, Nguyen HC, Matreyek KA, et al. (2014) Structural insight into HIV-1 restriction by MxB. Cell Host & Microbe. 16: 627-638
Matreyek KA, Yücel SS, Li X, et al. (2013) Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity. Plos Pathogens. 9: e1003693
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