Jared A. Wiig, Ph.D.

Affiliations: 
2013 Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Biochemistry
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"Jared Wiig"

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Markus W. Ribbe grad student 2013 UC Irvine
 (Elucidating the Roles of NifB and NifEN in Nitrogenase FeMoco Assembly.)
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Publications

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Fay AW, Wiig JA, Lee CC, et al. (2015) Identification and characterization of functional homologs of nitrogenase cofactor biosynthesis protein NifB from methanogens. Proceedings of the National Academy of Sciences of the United States of America. 112: 14829-33
Wiig JA, Hu Y, Ribbe MW. (2015) Refining the pathway of carbide insertion into the nitrogenase M-cluster. Nature Communications. 6: 8034
Cahn JK, Brinkmann-Chen S, Spatzal T, et al. (2015) Cofactor specificity motifs and the induced fit mechanism in Class I ketol-acid reductoisomerases. The Biochemical Journal
Rupnik K, Lee CC, Wiig JA, et al. (2014) Nonenzymatic synthesis of the P-cluster in the nitrogenase MoFe protein: evidence of the involvement of all-ferrous [Fe4S4](0) intermediates. Biochemistry. 53: 1108-16
Lee CC, Wiig JA, Hu Y, et al. (2014) Structures and Functions of the Active Sites of Nitrogenases Bioinspired Catalysis: Metal-Sulfur Complexes. 199-224
Wiig JA, Lee CC, Hu Y, et al. (2013) Tracing the interstitial carbide of the nitrogenase cofactor during substrate turnover. Journal of the American Chemical Society. 135: 4982-3
Wiig JA, Hu Y, Lee CC, et al. (2012) Radical SAM-dependent carbon insertion into the nitrogenase M-cluster. Science (New York, N.Y.). 337: 1672-5
Rupnik K, Hu Y, Lee CC, et al. (2012) P+ state of nitrogenase p-cluster exhibits electronic structure of a [Fe4S4]+ cluster. Journal of the American Chemical Society. 134: 13749-54
Fay AW, Lee CC, Wiig JA, et al. (2011) Protocols for cofactor isolation of nitrogenase. Methods in Molecular Biology (Clifton, N.J.). 766: 239-48
Wiig JA, Lee CC, Fay AW, et al. (2011) Purification of nitrogenase proteins. Methods in Molecular Biology (Clifton, N.J.). 766: 93-103
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