Shannon K. O'Neill, Ph.D.

Affiliations: 
2005 Rush University, Chicago, IL, United States 
Area:
Immunology
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"Shannon O'Neill"

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Alison Finnegan grad student 2005 Rush University
 (B cells play a critical role in the development of experimental autoimmune arthritis.)
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Publications

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Veselits M, Tanaka A, Chen Y, et al. (2017) Igβ ubiquitination activates PI3K signals required for endosomal sorting. The Journal of Experimental Medicine
Smith MJ, Packard TA, O'Neill SK, et al. (2017) Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function. Journal of Visualized Experiments : Jove
Smith MJ, Packard TA, O'Neill SK, et al. (2015) Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients. Diabetes. 64: 1703-12
Veselits M, Tanaka A, Lipkowitz S, et al. (2014) Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes. Plos One. 9: e89792
O'Neill SK, Getahun A, Gauld SB, et al. (2011) Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity. 35: 746-56
Getahun A, O'Neill SK, Cambier JC. (2009) Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. Journal of Immunology (Baltimore, Md. : 1950). 183: 5439-41
O'Neill SK, Liu E, Cambier JC. (2009) Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 293-8
O'Neill SK, Veselits ML, Zhang M, et al. (2009) Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6262-7
O'Neill SK, Cao Y, Hamel KM, et al. (2007) Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis. Journal of Immunology (Baltimore, Md. : 1950). 179: 5109-16
Zhang M, Veselits M, O'Neill S, et al. (2007) Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor. Journal of Immunology (Baltimore, Md. : 1950). 179: 4435-43
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