Keith M. Hamel, Ph.D.

Affiliations: 
2009 Rush University, Chicago, IL, United States 
Area:
Immunology
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"Keith Hamel"

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Alison Finnegan grad student 2009 Rush University
 (Roles of B cells in the development and progression of proteoglycan-induced arthritis.)
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Publications

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Veselits M, Tanaka A, Chen Y, et al. (2017) Igβ ubiquitination activates PI3K signals required for endosomal sorting. The Journal of Experimental Medicine
Mandal M, Hamel KM, Maienschein-Cline M, et al. (2015) Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nature Immunology
Olalekan SA, Cao Y, Hamel KM, et al. (2015) B cells expressing IFN-γ suppress Treg-cell differentiation and promote autoimmune experimental arthritis. European Journal of Immunology. 45: 988-98
Hamel KM, Mandal M, Karki S, et al. (2014) Balancing Proliferation with Igκ Recombination during B-lymphopoiesis. Frontiers in Immunology. 5: 139
Hamel KM, Cao Y, Olalekan SA, et al. (2014) B cell-specific expression of inducible costimulator ligand is necessary for the induction of arthritis in mice. Arthritis & Rheumatology (Hoboken, N.J.). 66: 60-7
Finnegan A, Ashaye S, Hamel KM. (2012) B effector cells in rheumatoid arthritis and experimental arthritis. Autoimmunity. 45: 353-63
Hamel KM, Liarski VM, Clark MR. (2012) Germinal center B-cells. Autoimmunity. 45: 333-47
Mandal M, Powers SE, Maienschein-Cline M, et al. (2011) Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nature Immunology. 12: 1212-20
Hamel KM, Cao Y, Ashaye S, et al. (2011) B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis Journal of Immunology. 187: 4900-4906
Hamel KM, Cao Y, Wang Y, et al. (2010) B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis. European Journal of Immunology. 40: 3117-27
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