Juan R. Cubillos-Ruiz, Ph.D.

Affiliations: 
2010 Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Immunology, Molecular Biology, Oncology
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"Juan Cubillos-Ruiz"

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Jose R. Conejo-Garcia grad student 2010 Dartmouth
 (Re-programming tumor-infiltrating dendritic cells in situ via RNAi elicits therapeutic immunity against ovarian cancer.)
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Publications

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Paffenholz SV, Salvagno C, Ho YJ, et al. (2022) Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 119
Salvagno C, Cubillos-Ruiz JR. (2021) Optineurin Guards IFNγ Signaling in Cancer Cells. Cancer Discovery. 11: 1623-1625
Chen X, Cubillos-Ruiz JR. (2020) Endoplasmic reticulum stress signals in the tumour and its microenvironment. Nature Reviews. Cancer
Payne KK, Mine JA, Biswas S, et al. (2020) BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. Science (New York, N.Y.). 369: 942-949
Mohamed E, Sierra RA, Trillo-Tinoco J, et al. (2020) The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 52: 668-682.e7
Cubillos-Ruiz JR. (2020) Abstract IA16: ER stress responses shape the ovarian cancer immune-microenvironment Clinical Cancer Research. 26
Salvagno C, Cubillos-Ruiz JR. (2019) The impact of endoplasmic reticulum stress responses in dendritic cell immunobiology. International Review of Cell and Molecular Biology. 349: 153-176
Cao Y, Trillo-Tinoco J, Sierra RA, et al. (2019) Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 3680
Giovanelli P, Sandoval TA, Cubillos-Ruiz JR. (2019) Dendritic Cell Metabolism and Function in Tumors. Trends in Immunology. 40: 699-718
Cao Y, Trillo-Tinoco J, Sierra RA, et al. (2019) ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 1280
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