Yashodhara Dasgupta, Ph.D.
Affiliations: | 2014 | Biology | Temple University, Philadelphia, PA, United States |
Area:
Cell Biology, OncologyGoogle:
"Yashodhara Dasgupta"Parents
Sign in to add mentor| Tomasz Skorski | grad student | 2014 | Temple University | |
| (Normal ABL1 is a tumor suppressor and therapeutic target in BCR-ABL1-positive leukemias.) | ||||
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Publications
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| Sullivan-Reed K, Bolton-Gillespie E, Dasgupta Y, et al. (2018) Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells. Cell Reports. 23: 3127-3136 |
| Maifrede S, Nieborowska-Skorska M, Sullivan K, et al. (2018) Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors. Blood |
| Dasgupta Y, Golovine K, Nieborowska-Skorska M, et al. (2017) Drugging DNA repair to target T-ALL cells. Leukemia & Lymphoma. 1-4 |
| Nieborowska-Skorska M, Maifrede S, Dasgupta Y, et al. (2017) Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms. Blood |
| Maifrede S, Martin K, Podszywalow-Bartnicka P, et al. (2017) IGH/MYC Translocation Associates with BRCA2 Deficiency and Synthetic Lethality to PARP1 Inhibitors. Molecular Cancer Research : McR |
| Nieborowska-Skorska M, Sullivan K, Dasgupta Y, et al. (2017) Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. The Journal of Clinical Investigation |
| Dasgupta Y, Koptyra M, Hoser G, et al. (2016) Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases. Blood |
| Maifrede S, Martin K, Podszywalow-Bartnicka P, et al. (2016) IGH/MYC Translocation in Burkitt Lymphoma Is Associated with BRCA2 Deficiency and Synthetic Lethality By PARP1 Inhibitors Blood. 128: 4111-4111 |
| Podszywalow-Bartnicka P, Wolczyk M, Kusio-Kobialka M, et al. (2014) Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation. Cell Cycle (Georgetown, Tex.). 13: 3727-41 |
| Podszywalow-Bartnicka P, Wolczyk M, Kusio-Kobialka M, et al. (2014) Downregulation of BRCA1 Protein in BCR-ABL1–positive Cells Depends on Tiar-Mediated Repression of BRCA1 mRNA Translation Blood. 124: 3129-3129 |