Jared D. Pitts, Ph.D.

Affiliations: 
2014 Molecular Microbiology Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Microbiology Biology, Virology Biology
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"Jared Pitts"

Parents

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Ekaterina Heldwein grad student 2014 Sackler School of Graduate Biomedical Sciences (Tufts University)
 (Biochemical and Structural Characterization of Proteins of the Herpesvirus Inner Tegument.)
Priscilla L. Yang post-doc Harvard (Chemistry Tree)
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Publications

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Vermillion MS, Murakami E, Ma B, et al. (2021) Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection. Science Translational Medicine. eabl828
Mackman RL, Hui HC, Perron M, et al. (2021) Prodrugs of a 1'-CN-4-Aza-7,9-dideazaadenosine -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV. Journal of Medicinal Chemistry
Koenigsberg AL, Pitts JD, Heldwein EE. (2020) Identification of Buffer Conditions for Optimal Thermostability and Solubility of Herpesviral Protein UL37 Using the Thermofluor Assay. Bio-Protocol. 10: e3662
Pruijssers AJ, George AS, Schäfer A, et al. (2020) Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Reports. 107940
Pruijssers AJ, George AS, Schäfer A, et al. (2020) Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice. Biorxiv : the Preprint Server For Biology
Pitts J, Hsia CY, Lian W, et al. (2019) Identification of small molecule inhibitors targeting the Zika virus envelope protein. Antiviral Research
Li PC, Jang J, Hsia CY, et al. (2019) Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo. Acs Infectious Diseases
de Wispelaere M, Lian W, Potisopon S, et al. (2018) Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology
Richards AL, Sollars PJ, Pitts JD, et al. (2017) The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion. Plos Pathogens. 13: e1006741
Pitts JD, Li PC, de Wispelaere M, et al. (2017) Antiviral activity of fenretinide against Zika virus. Antiviral Research
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