Jenish R. Patel, Ph.D.

Affiliations: 
2013 Microbiology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology, Genetics, Virology Biology
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"Jenish Patel"

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Ana F. Sesma grad student 2013 Mount Sinai School of Medicine
 (Activation of cytosolic pathogen sensor Retinoic Acid-inducible Gene I.)
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Publications

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Singh N, Ranjan P, Cao W, et al. (2020) A Dual-Functioning 5'-PPP-NS1shRNA that Activates a RIG-I Antiviral Pathway and Suppresses Influenza NS1. Molecular Therapy. Nucleic Acids. 19: 1413-1422
Aguirre S, Luthra P, Sanchez-Aparicio MT, et al. (2017) Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection. Nature Microbiology. 2: 17037
Hofstetter AR, De La Cruz JA, Cao W, et al. (2016) NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice. Plos One. 11: e0149864
Lässig C, Matheisl S, Sparrer KM, et al. (2015) ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA. Elife. 4
Spengler JR, Patel JR, Chakrabarti AK, et al. (2015) RIG-I mediates an antiviral response to Crimean-Congo hemorrhagic fever virus. Journal of Virology
Patel JR, García-Sastre A. (2014) Activation and regulation of pathogen sensor RIG-I. Cytokine & Growth Factor Reviews. 25: 513-23
Rajsbaum R, Versteeg GA, Schmid S, et al. (2014) Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response. Immunity. 40: 880-95
Sharma S, Mayank AK, Nailwal H, et al. (2014) Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α-actinin-4 for viral replication. The Febs Journal. 281: 2899-914
Schmolke M, Patel JR, de Castro E, et al. (2014) RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection. Mbio. 5: e01006-14
Patel JR, García-Sastre A. (2014) Three-stranded antiviral attack. Elife. 3: e02369
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