Ian Anthony James Lorimer

Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Biochemistry, Cell Biology, Oncology
"Ian Anthony James Lorimer"



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Bishnu D. Sanwal grad student 1989 Western Ontario (Chemistry Tree)
 (Regulation of cAMP-dependent protein kinases during skeletal myogenesis.)
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Jahani-Asl A, Yin H, Soleimani VD, et al. (2016) Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nature Neuroscience
Restall IJ, Parolin DA, Daneshmand M, et al. (2015) PKCι DEPLETION INITIATES MITOTIC SLIPPAGE-INDUCED SENESCENCE IN GLIOBLASTOMA. Cell Cycle (Georgetown, Tex.). 0
Lorimer IA. (2015) Atypical PKCι as target for glioblastoma therapy. Current Cancer Drug Targets. 15: 136-44
Gont A, Hanson JE, Lavictoire SJ, et al. (2014) Inhibition of glioblastoma malignancy by Lgl1. Oncotarget. 5: 11541-51
Karapetis CS, Jonker D, Daneshmand M, et al. (2014) PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 744-53
Goss GD, O'Callaghan C, Lorimer I, et al. (2013) Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3320-6
Liwak U, Jordan LE, Von-Holt SD, et al. (2013) Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation. Oncotarget. 4: 1365-72
Gont A, Hanson JE, Lavictoire SJ, et al. (2013) PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1. Oncotarget. 4: 1266-79
Hilton J, Weberpals J, Lorimer I, et al. (2012) BRCA1 protein levels and PIK3CA mutations as predictive biomarkers for response to neoadjuvant chemotherapy in locally advanced breast cancer: An exploratory analysis. Oncology Letters. 4: 141-145
Paget JA, Restall IJ, Daneshmand M, et al. (2012) Repression of cancer cell senescence by PKCι. Oncogene. 31: 3584-96
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