Greg Hussack, Ph.D.

Affiliations: 
2011 Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Microbiology Biology, Immunology, Toxicology
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"Greg Hussack"

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Jamshid Tanha grad student 2011 University of Ottawa
 (Single-domain Antibody Inhibitors of Clostridium difficile Toxins.)
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Publications

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Martina M, Banderali U, Yogi A, et al. (2024) A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2405432
Lei EK, Azmat A, Henry KA, et al. (2024) Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens. Applied Microbiology and Biotechnology. 108: 232
Aguilar EN, Sagar S, Murray BR, et al. (2024) Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Molecular Cancer Therapeutics
Kim DY, Kandalaft H, Lowden MJ, et al. (2023) Sequence tolerance of immunoglobulin variable domain framework regions to non-canonical intradomain disulfide linkages. The Journal of Biological Chemistry. 105278
Lowden MJ, Lei EK, Hussack G, et al. (2023) Applications of High-Throughput DNA Sequencing to Single-Domain Antibody Discovery and Engineering. Methods in Molecular Biology (Clifton, N.J.). 2702: 489-540
Rossotti MA, Trempe F, van Faassen H, et al. (2023) Isolation and Characterization of Single-Domain Antibodies from Immune Phage Display Libraries. Methods in Molecular Biology (Clifton, N.J.). 2702: 107-147
Lei EK, Ryan S, van Faassen H, et al. (2023) Isolation and characterization of a VHH targeting the Acinetobacter baumannii cell surface protein CsuA/B. Applied Microbiology and Biotechnology. 1-14
Hussack G, Rossotti MA, van Faassen H, et al. (2023) Corrigendum: Structure-guided design of a potent toxin A inhibitor. Frontiers in Microbiology. 14: 1167817
Hussack G, Rossotti MA, van Faassen H, et al. (2023) Structure-guided design of a potent toxin A inhibitor. Frontiers in Microbiology. 14: 1110541
Sheff J, Kelly J, Foss M, et al. (2022) Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction. Journal of Biochemistry
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