Scott McComb, Ph.D.

Affiliations: 
2013 Biochimie, microbiologie et immunologie / Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
Immunology, Cell Biology
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"Scott McComb"

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Subash Sad grad student 2013 University of Ottawa
 (The Paradoxical Roles of Cell Death Pathways in Immune Cells.)
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Publications

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Aguadé-Gorgorió J, McComb S, Eckert C, et al. (2020) TNFR2 is required for RIP1-dependent cell death in human leukemia. Blood Advances. 4: 4823-4833
Bloemberg D, Nguyen T, MacLean S, et al. (2020) A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells. Molecular Therapy. Methods & Clinical Development. 16: 238-254
McComb S, Chan PK, Guinot A, et al. (2019) Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7. Science Advances. 5: eaau9433
Chopra K, Alasmar S, Zafer A, et al. (2019) Improving The Cryopreservation Of Human Induced Pluripotent Stem Cells (Ipscs) And Human T-Cells With Ice Recrystallization Inhibitors (Iris) Cryobiology. 91: 162
Rijal D, Ariana A, Wight A, et al. (2018) Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1. The Journal of Biological Chemistry
Tripolitsioti D, Kumar KS, Neve A, et al. (2018) MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells. Oncotarget. 9: 23220-23236
Alturki NA, McComb S, Ariana A, et al. (2018) Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592
Jordi M, Marty J, Mordasini V, et al. (2017) IRAK4 is essential for TLR9-induced suppression of Epstein-Barr virus BZLF1 transcription in Akata Burkitt's lymphoma cells. Plos One. 12: e0186614
Aguadé-Gorgorio J, McComb S, Eckert C, et al. (2017) Abstract 4321: TNF receptor 2 is essential for RIP1-dependent cell death in refractory leukemia Cancer Research. 77: 4321-4321
Aguadé-Gorgorió J, McComb S, Dobay M, et al. (2017) Die another way: necroptosis as alternative route to cell death Klinische Padiatrie. 229
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