Glen A. Farr, Ph.D.

Affiliations: 
2005 Yale University, New Haven, CT 
Area:
Microbiology Biology, Cell Biology, Molecular Biology
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"Glen Farr"

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Peter Tattersall grad student 2005 Yale
 (The capsid five -fold cylinder and the VP1 N -terminal unique region are critical components of the parvoviral "entry machine".)
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Publications

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Farr GA, Hull M, Stoops EH, et al. (2015) Dual Pulse Chase Microscopy Reveals Early Divergence in the Biosynthetic Trafficking of the Na, K-ATPase and E-cadherin. Molecular Biology of the Cell
Stoops EH, Farr GA, Hull M, et al. (2014) SNAP-tag to monitor trafficking of membrane proteins in polarized epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 1174: 171-82
Alves DS, Farr GA, Seo-Mayer P, et al. (2010) AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression. Molecular Biology of the Cell. 21: 4400-8
Morton MJ, Farr GA, Hull M, et al. (2010) Association with {beta}-COP regulates the trafficking of the newly synthesized Na,K-ATPase. The Journal of Biological Chemistry. 285: 33737-46
Farr G, Santana Alves D, Stoops E, et al. (2010) Visualizing Protein Trafficking: Membrane Proteins Follow Multiple Trafficking Pathways to the Basolateral Cell Surface in Polarized Epithelial Cells Microscopy and Microanalysis. 16: 958-959
Farr GA, Hull M, Mellman I, et al. (2009) Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. The Journal of Cell Biology. 186: 269-82
Farr GA, Cotmore SF, Tattersall P. (2006) VP2 cleavage and the leucine ring at the base of the fivefold cylinder control pH-dependent externalization of both the VP1 N terminus and the genome of minute virus of mice. Journal of Virology. 80: 161-71
Farr GA, Zhang LG, Tattersall P. (2005) Parvoviral virions deploy a capsid-tethered lipolytic enzyme to breach the endosomal membrane during cell entry. Proceedings of the National Academy of Sciences of the United States of America. 102: 17148-53
Farr GA, Tattersall P. (2004) A conserved leucine that constricts the pore through the capsid fivefold cylinder plays a central role in parvoviral infection. Virology. 323: 243-56
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