Richard Virgen-Slane, Ph.D.

2013 Biomedical Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Virology Biology, Biochemistry, Molecular Biology
"Richard Virgen-Slane"


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Bert L. Semler grad student 2013 UC Irvine
 (DNA repair enzyme TDP2 moonlights as picornavirus VPg unlinkase.)
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Langereis MA, Feng Q, Nelissen FH, et al. (2014) Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Nucleic Acids Research. 42: 2473-82
Feng Q, Hato SV, Langereis MA, et al. (2012) MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells. Cell Reports. 2: 1187-96
Virgen-Slane R, Rozovics JM, Fitzgerald KD, et al. (2012) An RNA virus hijacks an incognito function of a DNA repair enzyme. Proceedings of the National Academy of Sciences of the United States of America. 109: 14634-9
Rozovics JM, Virgen-Slane R, Semler BL. (2011) Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity. Plos One. 6: e16559
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