Daniel C. Desrosiers, Ph.D.

2008 University of Connecticut, Storrs, CT, United States 
Biochemistry, Microbiology Biology
"Daniel Desrosiers"


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Justin Radolf grad student 2008 University of Connecticut
 (Protein-ligand interactions: (I) The study of an ankyrin repeat-mediated protein-protein interaction. (II) Metal specificities of the Tro and Znu transporters of Treponema pallidum, the syphilis spirochete.)
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Luthra A, Zhu G, Desrosiers DC, et al. (2011) The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices. The Journal of Biological Chemistry. 286: 41656-68
Eggers CH, Caimano MJ, Malizia RA, et al. (2011) The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host. Molecular Microbiology. 82: 679-97
Caimano MJ, Kenedy MR, Kairu T, et al. (2011) The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infection and Immunity. 79: 3117-30
Desrosiers DC, Anand A, Luthra A, et al. (2011) TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein. Molecular Microbiology. 80: 1496-515
Cox DL, Luthra A, Dunham-Ems S, et al. (2010) Surface immunolabeling and consensus computational framework to identify candidate rare outer membrane proteins of Treponema pallidum. Infection and Immunity. 78: 5178-94
Desrosiers DC, Bearden SW, Mier I, et al. (2010) Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence. Infection and Immunity. 78: 5163-77
Parsonage D, Desrosiers DC, Hazlett KR, et al. (2010) Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum. Proceedings of the National Academy of Sciences of the United States of America. 107: 6240-5
Earnhart CG, Leblanc DV, Alix KE, et al. (2010) Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment. Molecular Microbiology. 76: 393-408
Izard J, Renken C, Hsieh CE, et al. (2009) Cryo-electron tomography elucidates the molecular architecture of Treponema pallidum, the syphilis spirochete. Journal of Bacteriology. 191: 7566-80
Radolf JD, Desrosiers DC. (2009) Treponema pallidum, the stealth pathogen, changes, but how? Molecular Microbiology. 72: 1081-6
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