Matthew F. McCown, Ph.D.

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Virology Biology
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"Matthew McCown"

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Andrew Pekosz grad student 2006 Washington University
 (The influenza A virus M2 protein is a critical mediator of both virus assembly and disassembly.)
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Publications

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Grantham ML, McCown MF, Pekosz A. (2019) The Influenza A Virus M2 Protein -Complementation System Offers a Set of Tools for the Undergraduate Virology Laboratory. Journal of Microbiology & Biology Education. 20
Chua PK, McCown MF, Rajyaguru S, et al. (2009) Modulation of alpha interferon anti-hepatitis C virus activity by ISG15. The Journal of General Virology. 90: 2929-39
McCown MF, Rajyaguru S, Kular S, et al. (2009) GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796. Antimicrobial Agents and Chemotherapy. 53: 2129-32
Hang JQ, Yang Y, Harris SF, et al. (2009) Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus. The Journal of Biological Chemistry. 284: 15517-29
McCown MF, Rajyaguru S, Le Pogam S, et al. (2008) The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors. Antimicrobial Agents and Chemotherapy. 52: 1604-12
McCown MF, Pekosz A. (2006) Distinct domains of the influenza a virus M2 protein cytoplasmic tail mediate binding to the M1 protein and facilitate infectious virus production. Journal of Virology. 80: 8178-89
McCown MF, Pekosz A. (2005) The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging. Journal of Virology. 79: 3595-605
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