Alexis N. LaCrue, Ph.D.
Affiliations: | 2007 | University of Missouri - Columbia, Columbia, MO, United States |
Area:
Parasitology Biology, Microbiology BiologyGoogle:
"Alexis LaCrue"Parents
Sign in to add mentor| Brenda T. Beerntsen | grad student | 2007 | University of Missouri - Columbia | |
| (Characterization of the sporozoite and erythrocytic stages (SES) protein.) | ||||
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Publications
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| Neelarapu R, Maignan JR, Lichorowic CL, et al. (2017) Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies. Journal of Medicinal Chemistry |
| Maignan JR, Lichorowic CL, Giarrusso J, et al. (2016) ICI 56,780 Optimization: Structural-Activity and Relationship Studies of 7-(2-phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity. Journal of Medicinal Chemistry |
| Cross RM, Flanigan DL, Monastyrskyi A, et al. (2014) Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. Journal of Medicinal Chemistry. 57: 8860-79 |
| Chen N, LaCrue AN, Teuscher F, et al. (2014) Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 58: 4773-81 |
| Sáenz FE, Lacrue AN, Cross RM, et al. (2013) 4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni. Antimicrobial Agents and Chemotherapy. 57: 6187-95 |
| Nilsen A, LaCrue AN, White KL, et al. (2013) Quinolone-3-diarylethers: a new class of antimalarial drug. Science Translational Medicine. 5: 177ra37 |
| Roberts RN, Schlarman MS, Kariuki MM, et al. (2013) Expression profile of the Plasmodium falciparum intra-erythrocytic stage protein, PF3D7_1363700. Malaria Journal. 12: 66 |
| Lacrue AN, Sáenz FE, Cross RM, et al. (2013) 4(1H)-Quinolones with liver stage activity against Plasmodium berghei. Antimicrobial Agents and Chemotherapy. 57: 417-24 |
| Schlarman MS, Roberts RN, Kariuki MM, et al. (2012) PFE0565w, a Plasmodium falciparum protein expressed in salivary gland sporozoites. The American Journal of Tropical Medicine and Hygiene. 86: 943-54 |
| Schlarman MS, Roberts RN, Kariuki MM, et al. (2012) Transcript and protein expression profile of PF11_0394, a Plasmodium falciparum protein expressed in salivary gland sporozoites. Malaria Journal. 11: 80 |