Ine Jorgensen, Ph.D.

2011 Molecular Genetics and Microbiology Duke University, Durham, NC 
Microbiology Biology, Cell Biology, Molecular Biology
"Ine Jorgensen"


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Raphael H. Valdivia grad student 2011 Duke
 (The Chlamydia trachomatis Protease CPAF Regulates Secreted Bacterial Effectors and Host Proteins Essential to Virulence.)
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Li L, Kovacs SB, Jørgensen I, et al. (2022) Role of Caspases and Gasdermin A during HSV-1 Infection in Mice. Viruses. 14
Jorgensen I, Rayamajhi M, Miao EA. (2017) Programmed cell death as a defence against infection. Nature Reviews. Immunology
Jorgensen I, Zhang Y, Krantz BA, et al. (2016) Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. The Journal of Experimental Medicine
Finethy R, Jorgensen I, Haldar AK, et al. (2015) Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages. Infection and Immunity. 83: 4740-9
Jorgensen I, Miao EA. (2015) Pyroptotic cell death defends against intracellular pathogens. Immunological Reviews. 265: 130-42
Jorgensen I, Seed PC. (2012) How to make it in the urinary tract: a tutorial by Escherichia coli. Plos Pathogens. 8: e1002907
Bednar MM, Jorgensen I, Valdivia RH, et al. (2011) Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor. Biochemistry. 50: 7441-3
Jorgensen I, Bednar MM, Amin V, et al. (2011) The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host & Microbe. 10: 21-32
Jorgensen I, Valdivia RH. (2008) Pmp-like proteins Pls1 and Pls2 are secreted into the lumen of the Chlamydia trachomatis inclusion. Infection and Immunity. 76: 3940-50
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